HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Furancarboxylic acid, 5-methyl- → 2-Methyl-N-(5-methylfuran-2-yl)propanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Furancarboxylic acid, 5-methyl- | HCID 74710 | — |
| Reactant | Carbamic acid, (5-methyl-2-furanyl)-, 1,1-dimethylethyl ester | HCID 10726590 | — |
| Product | 2-Methyl-N-(5-methylfuran-2-yl)propanamide | HCID 23341603 | — |
Reaction Steps
tert-Butyl-5-methyl-2-furylcarbamate, (mp 80° C, 24 g, 0.12 mole) prepared as in Example 1 from 5-methyl-2-furoic acid was reacted as in Example 2 to give 2-isobutanamido-5-methylfuran (13.4 g) mp 78° C which was then reacted as in Example 4 to give the title compound. b.p. 94° C/0.3 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04082771 |
| Source dataset | uspto-grants-1978_04 |
| ORD ID | ord-e6389c88227a49b18b5da1d8a9f470ab |
| Source note | uspto-grants-1978_04 |