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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2082819Generated: November 1, 2026

3-(3-Amino-4-chlorobenzoyl)propionic acid → 3-(4-Chloro-3-hydroxybenzoyl)propionic acid

https://huagongshe.com/reaction/2082819

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Amino-4-chlorobenzoyl)propionic acidHCID 14256802—
ReactantSodium NitriteHCID 23668193—
SolventSulfuric AcidHCID 1118—
Product3-(4-Chloro-3-hydroxybenzoyl)propionic acidHCID 20360737—

Reaction Steps

3-(3-amino-4-chlorobenzoyl)propionic acid was diagotised in sulphuric acid solution with sodium nitrite and the diazonium salt solution was added dropwise to boiling aqueous sulphuric acid to give 3-(4-chloro-3-hydroxybenzoyl)propionic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04082843
Source datasetuspto-grants-1978_04
ORD IDord-29219bd9ba014cc381d11e2c1dd87ee8
Source noteuspto-grants-1978_04