Sulfuric Acid → HCID 20360789, compound

HRID 2082838Notes

Reaction equation

HRID 2082838 reaction equation
N[C:2]1[C:3]([CH3:15])=[C:4]([CH:12]=[CH:13][CH:14]=1)[C:5]([CH2:7][CH2:8][C:9]([OH:11])=[O:10])=[O:6].S(=O)(=O)(O)[OH:17].N([O-])=O.[Na+]>>[OH:17][C:2]1[C:3]([CH3:15])=[C:4]([CH:12]=[CH:13][CH:14]=1)[C:5]([CH2:7][CH2:8][C:9]([OH:11])=[O:10])=[O:6]

Participants

4

Reactant 3

HCID 1118Sulfuric Acid2×HCID 20360795HCID 20360795, compoundHCID 23668193Sodium Nitrite

Product 1

HCID 20360789HCID 20360789, compound

Procedure

3-(3-amino-2-methylbenzoyl)propionic acid was diazotised in a solution of sulphuric acid with sodium nitrite, and the diazonium salt solution was added dropwise to boiling aqueous sulphuric acid to give 3-(3-hydroxy-2-methylbenzoyl)proprionic acid.

Sources & evidence

ORD record
ord-7844a818a0624d53ac50dee723b7da40
Source dataset
uspto-grants-1978_04
Patent number
US04082843

Reaction notes

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