Potassium Hydroxide → HCID 12292310, compound

HRID 2082850Notes

Reaction equation

C([O:3][C:4]([C:6]1[CH:25]=[CH:24][C:23]([Cl:26])=[CH:22][C:7]=1[CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([CH2:16][C:17]([O:19]CC)=[O:18])=[CH:12][CH:11]=1)=[O:5])C.[OH-].[K+]>>[C:4]([C:6]1[CH:25]=[CH:24][C:23]([Cl:26])=[CH:22][C:7]=1[CH2:8][O:9][C:10]1[CH:11]=[CH:12][C:13]([CH2:16][C:17]([OH:19])=[O:18])=[CH:14][CH:15]=1)([OH:5])=[O:3]

Participants

Reactant 2

HCID 14797Potassium Hydroxide

HCID 21269142HCID 21269142, compound

Product 1

HCID 12292310HCID 12292310, compound

Procedure

Reaction of ethyl 4-(2-ethoxycarbonyl-5-chlorobenzyloxy)phenylacetate with potassium hydroxide as described in Example 1c provides 4-(2-carboxy-5-chlorobenzyloxy)phenylacetic acid as a colorless solid, mp 197°-201° C.

Sources & evidence

ORD record: ord-637860a279d64cf2aa4c0f447732dee3
Source dataset: uspto-grants-1978_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04082850

Reaction notes

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