Dichloromethane → 3-[1-(5-Fluoro-2-hydroxyphenyl)cycloprop-1-yl]-1-(2-methylquinolin-5-ylamino)-2-(trifluoromethyl)propan-2-ol
Reaction equation
[B:33]([Br:34])([Br:35])[Br:36].[Cl:37][CH2:38][Cl:39].[F:1][c:2]1[cH:3][cH:4][c:5]([O:31][CH3:32])[c:6]([C:8]2([CH2:11][C:12]([CH2:13][NH:14][c:15]3[c:16]4[cH:17][cH:18][c:19]([CH3:25])[n:20][c:21]4[cH:22][cH:23][cH:24]3)([OH:26])[C:27]([F:28])([F:29])[F:30])[CH2:9][CH2:10]2)[cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([OH:31])[c:6]([C:8]2([CH2:11][C:12]([CH2:13][NH:14][c:15]3[c:16]4[cH:17][cH:18][c:19]([CH3:25])[n:20][c:21]4[cH:22][cH:23][cH:24]3)([OH:26])[C:27]([F:28])([F:29])[F:30])[CH2:9][CH2:10]2)[cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-1288809204374eaea2dd5ddcf2d048e5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…