3-Butylamino-4-phenoxy-5-sulphamyl-benzamide → HCID 57105491, compound

HRID 2082882Notes

Reaction equation

HRID 2082882 reaction equation
[CH2:1]([NH:5][C:6]1[CH:7]=[C:8]([CH:12]=[C:13]([S:22](=[O:25])(=[O:24])[NH2:23])[C:14]=1[O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:9](N)=O)[CH2:2][CH2:3][CH3:4].[CH2:26]([NH:30]C1C=C(C=C(S(=O)(=O)N)C=1OC1C=CC=CC=1)C(NC)=O)CCC>>[CH2:1]([NH:5][C:6]1[CH:7]=[C:8]([CH:12]=[C:13]([S:22](=[O:25])(=[O:24])[NH2:23])[C:14]=1[O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH2:9][CH2:26][NH2:30])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 215060653-Butylamino-4-phenoxy-5-sulphamyl-benzamideHCID 54548785HCID 54548785, compound

Product 1

HCID 57105491HCID 57105491, compound

Procedure

By replacing in Example 289 3-n-butylamino-4-phenoxy-5-sulfamylbenzamide with an equimolar amount of 3-n-butylamino-4-phenoxy-5-sulfamyl-N-methylbenzamide and following the procedure described, (3-n-butylamino-4-phenoxy-5-sulfamylbenzyl)methylamine is obtained with a melting point of 157°-159° C. The material (IR, analysis) is identical with the material prepared as in Example 115.

Sources & evidence

ORD record
ord-4e2b50aa41e14ab487b14bf4ff7fc0e3
Source dataset
uspto-grants-1978_04
Patent number
US04082851

Reaction notes

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