3,3-Dimethylspiro[cyclopropane-1,1'-indene]-2-carboxylic acid → ethyl 3,3-dimethylspiro(cyclopropane-1,1'-(1H)indene)-2-carboxylate

HRID 2082960Notes

Reaction equation

HRID 2082960 reaction equation
[SH+]1CCCC1.[CH3:6][C:7]1([CH3:35])[C:9]2([C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH:11]=[CH:10]2)[CH:8]1[C:18]([O:20][CH2:21][C:22]1C=CC=C(OC2C=CC=CC=2)C=1)=[O:19].CC1(C)C2(C3C(=CC=CC=3)C=C2)C1C(O)=O>>[CH3:6][C:7]1([CH3:35])[C:9]2([C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH:11]=[CH:10]2)[CH:8]1[C:18]([O:20][CH2:21][CH3:22])=[O:19]

Participants

4

Reactant 3

HCID 1084553,3-Dimethylspiro[cyclopropane-1,1'-indene]-2-carboxylic acidHCID 128823303,3-Dimethylspiro[cyclopropane-1,1'-indene]-2-carboxylic acid, m-phenoxybenzyl esterHCID 21954569Tetrahydrothiophenium2×

Product 1

HCID 6455154ethyl 3,3-dimethylspiro(cyclopropane-1,1'-(1H)indene)-2-carboxylate

Procedure

By the above procedure, but substituting tetrahydrothiophenium carboxymethylide-, m-phenoxybenzyl ester and tetrahydrothiophenium carboxymethylide-, 3,3-dimethylspiro[cyclopropane-1,1'-indene]-2-carboxylic acid, m-phenoxybenzyl ester and 3,3-dimethylspiro[cyclopropane-1,1'-indene]-2-carboxylic acid, are obtained, respectively.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-de4a95ac491c473793e9c79dc9ec1c75
Source dataset
uspto-grants-1978_04
Patent number
US04083863

Reaction notes

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