HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl N-(C-methoxycarbonimidoyl)carbamate → N-carbethoxy-N'-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]guanidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl N-(C-methoxycarbonimidoyl)carbamate | HCID 149151130 | — |
| Reactant | HCID 178433288 | HCID 178433288 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-carbethoxy-N'-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]guanidine | HCID 178473547 | — |
Reaction Steps
A solution of N-carbethoxy-O-methylisourea (1.46 g.) and 4-methyl-5-((2-aminoethyl)thiomethyl)imidazole (1.71 g.) in methanol (25 ml) was stirred at room temperature for 7 days. The white solid formed during the reaction was collected and recrystallised from methanol to give N-carbethoxy-N'-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]guanidine m.p. 196°-197°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04083988 |
| Source dataset | uspto-grants-1978_04 |
| ORD ID | ord-5bb308a1e642477eb60984e8f4553c23 |
| Source note | uspto-grants-1978_04 |