HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Amino-1-hexanol → 1-(6-Hydroxyhexyl)-1-methylamino-2-nitroethylene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Amino-1-hexanol | HCID 19960 | — |
| Reactant | 1-Methylthio-1-methylamino-2-nitroethylene | HCID 123549 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(6-Hydroxyhexyl)-1-methylamino-2-nitroethylene | HCID 86735616 | — |
Reaction Steps
A mixture of 6-aminohexan-1-ol and 1-methylamino-1-methylthio-2-nitroethylene in ethanol is heated on a steam-bath to give 1-(6-hydroxyhexyl)-1-methylamino-2-nitroethylene. Substitution of 1-(6-hydroxyhexyl)-1-methylamino-2-nitroethylene for N-cyano-N'-(5-hydroxypentyl)-N"-methylguanidine in the procedure of Example 5 (ii and iii) leads to the production of S-[6-((1-methylamino-2-nitrovinyl)amino)hexyl]isothiourea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04084001 |
| Source dataset | uspto-grants-1978_04 |
| ORD ID | ord-a8c314382c754386a739cdffcd503d16 |
| Source note | uspto-grants-1978_04 |