HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → 2',4,4',5-Tetrachloropyrrole-2-carboxanilide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | 2,4-Dichloroaniline | HCID 11123 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4,5-Dichloro-1H-pyrrole-2-carboxylic acid | HCID 16227494 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 2',4,4',5-Tetrachloropyrrole-2-carboxanilide | HCID 20359876 | — |
Reaction Steps
4,5-Dichloropyrrole-2-carboxylic acid (10 g., 0.056 mole) was converted to the corresponding acid chloride by reaction with 15 ml. of thionyl chloride, and the acid chloride dissolved in 25 ml. of benzene was reacted with 9.2 g. (0.057 mole) of 2,4-dichloroaniline in 50 ml. of pyridine using the procedure described above in Example 3. The product was recrystallized from an ethyl acetate/ethanol mixture to give 10.0 of 2',4,4',5-tetrachloropyrrole-2-carboxanilide, m.p. 262°-264° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04084051 |
| Source dataset | uspto-grants-1978_04 |
| ORD ID | ord-d5c8cc3018eb4c09b3155c49d26e0e80 |
| Source note | uspto-grants-1978_04 |