HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-(beta-[2-Dimethylaminoethyl]phenethyl)benzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | HCID 20359294 | HCID 20359294 | — |
| Product | 2-(beta-[2-Dimethylaminoethyl]phenethyl)benzoic acid ethyl ester | HCID 53922756 | — |
Reaction Steps
A solution of 29.7 g. (0.1 mole) of 2-(β-[2-dimethylaminoethyl]phenethyl)benzoic acid in 200 ml. of ethanol is saturated with gaseous hydrochloride, and the resulting mixture is refluxed for 18 hours. The solvent is removed in vacuo and the residue is partitioned between ether and 2N sodium hydroxide. The ether extract is dried and evaporated in vacuo to give 2-(β-[2-dimethylaminoethyl]phenethyl)benzoic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04083997 |
| Source dataset | uspto-grants-1978_04 |
| ORD ID | ord-4d2c2dddf82740bc9b204298882a3193 |
| Source note | uspto-grants-1978_04 |