反应详情

Dibutylphosphorochloridate (3.74 g) was added to a solution of 2-(di-n-butyl methylsilyl)-ethanol (3 g) and pyridine (1.04 g) in carbon tetrachloride (10 ml). The mixture was left overnight, filtered, and the filtrate passed through an alumina column (20 g), eluting with a further 3 × 20 ml of carbon tetrachloride. Removal of the solvent under vacuum left the phosphate as a colourless oil (2.7 g).

1. filtrationfiltered
2. washeluting with a further 3 × 20 ml of carbon tetrachloride
3. customRemoval of the solvent under vacuum
4. waitleft the phosphate as a colourless oil (2.7 g)