反应详情

A mixture of 14 g. (0.1 mole) of N-acetyl-4-piperidinone and 32 g. (0.3 mole) of benzaldehyde in 150 ml. of ethanol containing 33 ml. of conc. HCl is refluxed for 6 hours and then kept overnight at room temperature. The light yellow solid is filtered, washed with ethanol, washed with ether, and air-dried to yield 26 g. of product; m.p. 273°-275° (dec.).

1. additionA mixture of 14 g
2. filtrationThe light yellow solid is filtered
3. washwashed with ethanol
4. washwashed with ether
5. customair-dried
6. customto yield 26 g