Ammonium Chloride → HCID 178514905, compound

Participants

Reaction Steps

A mixture of 4.8 g of 5-oxo-5H-[1]benzothiopyrano[2,3-b]pyridine-7-carbonitrile, 80 ml of dimethylformamide, 1.35 g. of ammonium chloride and 1.7 g of sodium azide is heated with stirring at 110° C to 120° C for 20 hours. After cooling, crystals are filtered off and added to a dilute hydrochloric acid, and the mixture is stirred. The crystals are filtered off, washed with water and recrystallized from dimethylformamide to give 3.8 g of 7-(5-1H-tetrazolyl)-5-oxo-5H-[1]benzothiopyrano[2,3-b]pyridine melting at above 300° C.

Provenance & Evidence