HCID 178423536, compound → HCID 178423535, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 1 g of 2-[2-methyl-4-(5-1H-tetrazolyl)phenoxy]nicotinic acid and 10 ml of concentrated sulfuric acid is heated at 180° C for 2.5 hours, and then poured into ice water. The crystalline precipitate is filtered off, washed with water and with methanol and recrystallized from dimethylformamide to give 0.5 g of 9-methyl-7-(5-1H-tetrazolyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine melting at 290° C to 291° C with decomposition.

Provenance & Evidence