Acetic Anhydride → 2-ethylsulfanylpyridine

HRID 2083258Notes

Reaction equation

[C:1](OC(=O)C)(=O)[CH3:2].[SH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1>>[CH2:1]([S:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1)[CH3:2]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 178418616HCID 178418616, compound

Product 1

HCID 4125432-ethylsulfanylpyridine

Procedure

d. 2-Ethylthio-pyridine was prepared by the same method as used for compound (1) c., except that ethyl halide was used instead of methyl halide. The product had a b.p. of 77°-77.5° C./8 mm. Hg. (1) e. (Pyridyl-2)-thiol acetate was prepared by reacting acetic anhydride with 2-mercaptopyridine in alkaline medium according to the method described in Houben-Weyl, 4th ed., vol. 9, 753 (1955) and in J.A.C.S. 59, 1089 (1937). The product has a b.p. of 117°-118° C./9 mm. Hg.

Sources & evidence

ORD record: ord-788b5fe6a9bb4ef3a9f3035b6540daf4
Source dataset: uspto-grants-1978_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04085109

Reaction notes

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