Methanethiol → Pyrazineethanethiol

HRID 2083259Notes

Reaction equation

HRID 2083259 reaction equation
[CH:1]([C:3]1[CH:8]=[N:7][CH:6]=[CH:5][N:4]=1)=[CH2:2].[CH3:9][SH:10].C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>>[N:4]1[CH:5]=[CH:6][N:7]=[CH:8][C:3]=1[CH2:1][CH2:2][SH:10].[CH3:9][S:10][CH2:2][CH2:1][C:3]1[CH:8]=[N:7][CH:6]=[CH:5][N:4]=1

Participants

5

Reactant 3

HCID 878MethanethiolHCID 7187Benzoyl PeroxideHCID 77840Vinylpyrazine2×

Product 2

HCID 61945PyrazineethanethiolHCID 226304002-Pyrazinyl-ethyl methyl sulfide

Procedure

g. 2-Pyrazinyl-ethyl mercaptan was prepared by reacting vinylpyrazine [obtained by the method described in J.Org.Chem. 27, 1363 (1962)] and hydrolizing the resulting thiolic acid ester according to the method described in J.Org.Chem. 22, 980 (1957). The product has a b.p. of 56.5°-60° C./0.003 mm. Hg. (1) h. 2-Pyrazinyl-ethyl methyl sulfide was prepared by reacting vinylpyrazine [c.f. J.Org.Chem. 27, 1363 (1962)] with methylmercaptan by the action of ultra violet light and in the presence of benzoyl peroxide by the method described in Acta Chem. Scand. 8, 295 (1954). The product was identified by mass spectrometry. It has a b.p. of 57°-69° C. at 0.05 mm. Hg.

Workup

  1. customobtained by the method

Sources & evidence

ORD record
ord-f5634c22e61643ce9158853d3fee17f9
Source dataset
uspto-grants-1978_04
Patent number
US04085109

Reaction notes

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