反应详情

Propanesultone (61g; 0.5 mole) was added to a stirred solution of n-butylamine (36.5g; 0.5 mole) in methanol (200 ml) in 10 min. The reaction temperature was kept at 50°-55° by cooling. After stirring 40 min, a white solid began to separate. After stirring overnight filtration yielded 3-butylaminopropylsulfonic acid 94g (96%).

1. customwas kept at 50°-55°
2. temperatureby cooling
3. customto separate
4. stirringAfter stirring overnight
5. filtrationfiltration