Ethyl bromoacetate → HCID 20358290, compound

Participants

Reaction Steps

To a solution of 10 g of 2-hydroxyacetophenone in 40 ml of acetone, 12 g of potassium carbonate was added, and after the mixture was agitated for 1 hour at room temperature, 14 g of bromoacetic acid ethyl ester was added dropwise while stirring, and the resultant mixture was agitated for 3 hours. The reaction mixture was filtered and acetone was evaporated, leaving a residue which was extracted with ether. Evaporation of ether left a residue, which was recrystallized from petroleum ether to give 9.7 g of 2-(ethoxycarbonylmethoxy)-acetophenone, m.p. 33°-35° C.

Provenance & Evidence