HCID 21317646, compound → HCID 21317564, compound

Participants

Reaction Steps

1-(2-Tetrahydropyranyloxy)-4-acetoxy-5-(3-trifluoromethylphenoxy)-2-pentyne (40.18 g.; 0.104 mole) is dissolved in ethyl acetate (200 ml.). 5% Palladium on carbon (5 g.) is added and the mixture is hydrogenated on the Parr apparatus at an initial pressure of 45 lbs./in2 and 25°. When 0.208 mole of hydrogen is absorbed, the catalyst is removed by filtration and the solvent is evaporated under vacuum to give the title compound as a light orange residual oil, yield 40.60 g.; pmr (CDCl3)δ2.13 (3H, s CH3COO), 4.10 (2H, d CH2O), 5.20 (1H, m CHOCO), 7.22 (4H, m Aryl H).

Provenance & Evidence