Isopropylamine → HCID 178457960, compound

HRID 2083371Notes

Reaction equation

HRID 2083371 reaction equation
[NH2:1][C:2]1[C:3]([C:10]([N:12]=[CH:13][NH:14][NH:15][C:16](C2NC=CN=2)=[O:17])=[O:11])=[N:4][C:5]([F:9])=[C:6]([NH2:8])[N:7]=1.[CH:23]([NH2:26])([CH3:25])[CH3:24]>>[NH2:1][C:2]1[C:3]([C:10]([N:12]=[CH:13][NH:14][NH:15][C:16]([NH:26][CH:23]([CH3:25])[CH3:24])=[O:17])=[O:11])=[N:4][C:5]([F:9])=[C:6]([NH2:8])[N:7]=1

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 178508799HCID 178508799, compound

Product 1

HCID 178457960HCID 178457960, compound

Procedure

Following the procedure of Example 54, Step B but substituting 3,5-diamino-6-fluoro-N-{[(imidazolcarbonyl)amino]aminomethylene}-2-pyrazinecarboxamide (1.3 g.) and isopropylamine (0.45 ml) in place of the corresponding reactants in Example 54, Step B there is obtained 3,5-diamino-6-fluoro-N-{[(isopropylaminocarbonyl)amino]aminomethylene}-2-pyrazinecarboxamide. Yield: 600 Mg. M.P. 221° C.

Sources & evidence

ORD record
ord-2bdca2378dbc47c987561f98d925d7aa
Source dataset
uspto-grants-1978_04
Patent number
US04085211

Reaction notes

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