Phosphorus sulfide (P2S5) → HCID 20358395, compound

Participants

Reaction Conditions

Reaction Steps

The amide (1 mol) is dissolved in dry pyridine saturated with H2S gas and treated with P2S5 (1 mol) then heated at reflux for 45 min. while maintaining a slow stream of H2S gas. The reaction mixture is evaporated to dryness in vacuo and cooled to 0° C, made alkaline with 10% sodium hydroxide and the solution extracted with chloroform (3 times). The combined extracts are washed with brine, dried and evaporated in vacuo to give the title compound.

Provenance & Evidence