HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 2-Ethyl-2-n-propyl-5-methoxy-6,7-dichloro-1-indanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1-Iodopropane | HCID 33643 | — |
| Reactant | 2-Ethyl-5-methoxy-6,7-dichloro-1-indanone | HCID 12395555 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 2-Ethyl-2-n-propyl-5-methoxy-6,7-dichloro-1-indanone | HCID 12395563 | — |
Reaction Steps
2-Ethyl-2-n-propyl-5-methoxy-6,7-dichloro-1-indanone is prepared following substantially the same procedure described in Example 5, Step E, using the following substances: 2-ethyl-5-methoxy-6,7-dichloro-1-indanone (13 g., 0.05 mole), sodium hydride (1.3 g., 0.055 mole), 1,2-dimethoxyethane (500 ml.) and n-propyliodide (6 ml.). The above procedure gives 6.0 g. of 2-ethyl-2-n-propyl-5-methoxy-6,7-dichloro-1-indanone which after recrystallization from ethanol melts at 92° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04085219 |
| Source dataset | uspto-grants-1978_04 |
| ORD ID | ord-852073325127432f9b6bf861d74cd473 |
| Source note | uspto-grants-1978_04 |