HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoacetic Acid → (1-Oxo-2,2,3-trimethyl-6,7-dichloro-5-indanyloxy)acetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoacetic Acid | HCID 5240 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,2,3-Trimethyl-5-hydroxy-6,7-dichloro1-indanone | HCID 20358468 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | (1-Oxo-2,2,3-trimethyl-6,7-dichloro-5-indanyloxy)acetic Acid | HCID 20358437 | — |
Reaction Steps
A mixture of 2,2,3-trimethyl-5-hydroxy-6,7-dichloro-1-indanone (6.1 g., 0.025 mole), iodoacetic acid (5.58 g., 0.03 mole) and potassium carbonate (4.14 g., 0.03 mole) in acetone (80 ml.) is refluxed for 20 hours. The acetone is evaporated and the residue is dissolved in water and acidified with hydrochloric acid. The (1-oxo-2,2,3-trimethyl-6,7-dichloro-5-indanyloxy)acetic acid which separates is filtered, rinsed with water and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04085219 |
| Source dataset | uspto-grants-1978_04 |
| ORD ID | ord-4be18314b9b143cc80d6715d1a542b2a |
| Source note | uspto-grants-1978_04 |