Isopropyl iodide → HCID 20357155, compound

Participants

Reaction Conditions

Reaction Steps

To a hot, stirred solution (50° C) of 20.0 g. of 4-nitrobenzotriazole in 600 ml. of acetonitrile is added 4.2 g. of sodium hydroxide pels and 20.0 g. of isopropyl iodide. The solution is then heated to reflux for 30 hours, filtered and the solvent removed by evaporation to yield an oil. The oil is extracted with concentrated hydrochloric acid (3 × 200 ml.) to leave behind a solid material. The solid is washed with water and air dried to yield crude 2-isopropyl-4-nitrobenzotriazole. The analytical sample is recrystallized from petroleum ether, m.p. 65°-67° C.

Provenance & Evidence