HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → 7-Bromobenzothiazol-2-yl isocyanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | 7-Bromo-1,3-benzothiazol-2-amine | HCID 20357112 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 7-Bromobenzothiazol-2-yl isocyanate | HCID 53646458 | — |
Reaction Steps
A saturated solution of phosgene in ethyl acetate (200 ml) is charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. 2-Amino-7-bromobenzothiazole (0.1 mole) is added with stirring. After this time the mixture is cooled, and the solid product formed is recovered by filtration. The solid is then dried to yield the desired product 7-bromobenzothiazol-2-yl isocyanate dimer.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04086241 |
| Source dataset | uspto-grants-1978_04 |
| ORD ID | ord-4cf6e1157416427ab74e3af5f352bdd9 |
| Source note | uspto-grants-1978_04 |