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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2083667Generated: October 31, 2026

4-Bromo-2,2-diphenylbutyronitrile → HCID 20356983, compound

https://huagongshe.com/reaction/2083667

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2,2-diphenylbutyronitrileHCID 96575—
ReactantPiperidine, hydrochloride (1:1)HCID 2723721—
Reactantα-(2-Chloroethyl)-α-ethylbenzeneacetonitrileHCID 13297921—
Reactant2-Azabicyclo[2.2.2]octane hydrochlorideHCID 21984844—
ProductHCID 20356983HCID 20356983—

Reaction Steps

When equivalent quantities of piperidine hydrochloride and 2-phenyl-2-(2-chloroethyl)butyronitrile are substituted for the 2-azabicyclo[2.2.2]octane hydrochloride and 2,2-diphenyl-4-bromobutyronitrile used in Example 12, and the procedure described therein substantially repeated, there is obtained 2-phenyl-2-ethyl-4-piperidino-butyronitrile hydrochloride melting at about 200° - 203° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04086234
Source datasetuspto-grants-1978_04
ORD IDord-7d2aaa71736f433182bfdec9b24da33b
Source noteuspto-grants-1978_04