3-Azabicyclo[3.2.2]nonane → HCID 20356970, compound

HRID 2083674Notes

Reaction equation

HRID 2083674 reaction equation
[C:1]1([C:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)([CH2:10][CH2:11][CH2:12][Cl:13])[C:8]#[N:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:20]12[CH2:28][CH2:27][CH:24]([CH2:25][CH2:26]1)[CH2:23][NH:22][CH2:21]2>>[ClH:13].[C:1]1([C:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)([CH2:10][CH2:11][CH2:12][N:22]2[CH2:23][CH:24]3[CH2:27][CH2:28][CH:20]([CH2:26][CH2:25]3)[CH2:21]2)[C:8]#[N:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 92403-Azabicyclo[3.2.2]nonaneHCID 3240195-chloro-2,2-diphenylpentanenitrile

Product 1

HCID 20356970HCID 20356970, compound

Procedure

Using an equivalent quantity of 2,2-diphenyl-5-chlorovaleronitrile in place of the 2,2-diphenyl-4-bromobutyronitrile, and 3-azabicyclo[3.2.2]nonane in place of the piperidine used in Example 22, and substantially repeating the procedure detailed therein, affords 2,2-diphenyl-5-(3-azabicyclo[3.2.2]non-3-yl)valeronitrile hydrochloride, melting at about 272° - 273° C. This compound is represented by the following structural formula. ##STR17##

Sources & evidence

ORD record
ord-91a1cb856e5a42db83809378cb3d3d0a
Source dataset
uspto-grants-1978_04
Patent number
US04086234

Reaction notes

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