Ethanolamine → HCID 20357536, compound

HRID 2083727Notes

Reaction equation

HRID 2083727 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[N:11]=[C:12]=S)[CH:4]=[N:3]1.[CH2:14]([CH2:16][NH2:17])[OH:15]>CCOCC>[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[NH:11][C:12]2[O:15][CH2:14][CH2:16][N:17]=2)[CH:4]=[N:3]1

Participants

4

Reactant 2

HCID 700EthanolamineHCID 203575387-Isothiocyanato-1-methyl-1H-indazole

Product 1

HCID 20357536HCID 20357536, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The starting material is prepared as follows: 3 g of 1-methyl-7-isothiocyanato-indazole is added to a stirred mixture of 2 ml of ethanolamine and 100 ml of ether, thus forming a white precipitate. After 2 hours the precipitate is filtered off and washed with ether to yield the starting material; M.Pt. 207° - 209°.

Workup

  1. customThe starting material is prepared
  2. customthus forming a white precipitate
  3. filtrationAfter 2 hours the precipitate is filtered off
  4. washwashed with ether
  5. customto yield the starting material

Sources & evidence

ORD record
ord-5e502b75df0b4d0aaee63fbe985baa8a
Source dataset
uspto-grants-1978_04
Patent number
US04086353

Reaction notes

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