HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Thiocarbonyldiimidazole → HCID 22731667, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Thiocarbonyldiimidazole | HCID 80264 | — |
| Reactant | HCID 22731670 | HCID 22731670 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22731667 | HCID 22731667 | 59% |
Reaction Steps
9.5 g of 1,1-thiocarbonyldiimidazole are added to 85 g of 4-(4′-ethylbicyclohexyl-4-yl)-2,6-difluorophenylamine in 100 ml of dichloromethane, and the mixture is stirred at RT. Conventional work-up gives 4′-(3,5-difluoro-4-isothiocyanatophenyl)-4-ethylbicyclohexyl, yield 59%, having the following properties: C 33 N 198.2 I; Δε 15.3; Δn 0.1930.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716491B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-a68cec149e5e4d029979c586e9a1ffb6 |
| Source note | uspto-grants-2004_04 |