HuagongsheHuagongshe Chemistry Print Report · For research reference only
Heptane → HCID 69835965, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Heptane | HCID 8900 | — |
| Reactant | HCID 22731980 | HCID 22731980 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 69835965 | HCID 69835965 | — |
Reaction Steps
The enantiomers of 6-chloro-4-hydroxy-8-methoxythiochromane-4-yl-carboxylic acid (3.00 g, 10.9 mmol; see step (v) above) were separated using chiral chromatography (Kromasil TBB; heptane:ethyl acetate:formnic acid) affording 1.13 g of the faster moving, not wanted S-enantiomer, and 1.19 g (79%) of the slower moving sub-title compound. ee=94.6%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716834B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-660d575f5d0d46c0998b0397d2868874 |
| Source note | uspto-grants-2004_04 |