HCID 13953832, compound → HCID 13953737, compound

HRID 2083908Notes

Reaction equation

HRID 2083908 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[S:9][CH2:10][CH2:11][C:12]([OH:14])=O>S(=O)(=O)(O)O>[Cl:8][C:6]1[CH:5]=[C:4]2[C:3](=[C:2]([Cl:1])[CH:7]=1)[S:9][CH2:10][CH2:11][C:12]2=[O:14]

Participants

3

Reactant 1

HCID 13953832HCID 13953832, compound

Product 1

HCID 13953737HCID 13953737, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

A deep red colour was immediately observed when 3-(2,4-dichlorophenylthio)propanoic acid (1.20 g, 4.78 mmol; from step (ii) above) was added to conc. sulfuric acid (30 mL). After stirring overnight at ambient temperature the reaction mixture was poured into ice. The red colour disappeared. Extraction with diethyl ether, washing with aq., sat. sodium hydrogencarbonate, drying (MgSO4) and removal of the solvent in vacuo afforded a deep yellow solid.

Workup

  1. additionwas poured into ice
  2. extractionExtraction with diethyl ether
  3. washwashing with aq., sat. sodium hydrogencarbonate
  4. customdrying
  5. custom(MgSO4) and removal of the solvent in vacuo
  6. customafforded a deep yellow solid

Sources & evidence

ORD record
ord-6b63d90ca96c4953b728478bb8f4d99e
Source dataset
uspto-grants-2004_04
Patent number
US06716834B2

Reaction notes

Loading…