Potassium Carbonate → HCID 22731993, compound

Participants

Reaction Steps

A slurry of N-(3-methoxy-2-methylphenyl)methanesulfonamide 7a (Blondet, D.; Pascal, J. -C. Tetrahedron Lett. 1994, 35, 2911) (4.5 g, 20.9 mmol), K2CO3 (4.33 g, 31.4 mmol) and Mel (6.52 mL, 105 mmol) in DMF (100 mL) was stirred vigorously for 5 days. The reaction was poured onto H2O (250 mL), stirred for 10 minutes and then extracted with ether. The combined organic extracts were washed with water and brine and dried over MgSO4 to give 7b (5.10 g) after removal of the solvent.

Provenance & Evidence