HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → (S)-N-[2-Amino-3-oxo-3-(1-pyrrolidinyl)propyl]-methane-sulphonamide Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | Boc-dap(Z)-OH | HCID 2755950 | — |
| Product | (S)-N-[2-Amino-3-oxo-3-(1-pyrrolidinyl)propyl]-methane-sulphonamide Hydrochloride | HCID 69891985 | — |
Reaction Steps
Starting from (S)-3-[(benzyloxycarbonyl)-amino]-2-[(tert-butyloxycarbonyl)-amino]-propanoic acid, methanesulphonyl chloride and pyrrolidine, the expected product is obtained according to the procedure described in Example 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716843B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-b2e9e7f90c664304922cfbd3a290303a |
| Source note | uspto-grants-2004_04 |