HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → (S)N-[3Amino4-oxo-4-(1-pyrrolidinyl)-butyl]-methanesulphonamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | (S)-4-(((Benzyloxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)butanoic acid | HCID 7019688 | — |
| Product | (S)N-[3Amino4-oxo-4-(1-pyrrolidinyl)-butyl]-methanesulphonamide hydrochloride | HCID 21304788 | — |
Reaction Steps
Starting from (S)-4-[(benzyloxycarbonyl)-amino]-2-[(tert-butyloxycarbonyl)-amino]-butanoic acid, methanesulphonyl chloride and pyrrolidine, the expected product is obtained according to the procedure described in Example 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716843B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-9219d217fc85420ca0d3520172670c49 |
| Source note | uspto-grants-2004_04 |