HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiazolidine → (S)-N-{2-[2-Amino-3-oxo-3-(1,3-thiazolidin-3-yl)propylthio]-ethyl}-methanesulphonamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiazolidine | HCID 10444 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | (S)-3-(2-{[benzyloxycarbonyl]-amino}-ethylthio)-N-(tert-butyloxy-carbonyl)-alanine | HCID 11409801 | — |
| Product | (S)-N-{2-[2-Amino-3-oxo-3-(1,3-thiazolidin-3-yl)propylthio]-ethyl}-methanesulphonamide hydrochloride | HCID 69891997 | — |
Reaction Steps
Starting from (S)-3-(2-{[benzyloxycarbonyl]-amino}-ethylthio)-N-(tert-butyloxy-carbonyl)-alanine, methanesulphonyl chloride and 1,3-thiazolidine, the expected product is obtained according to the procedure described in Example 37.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716843B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-efa9d10bedac44deaf25d2cb35396961 |
| Source note | uspto-grants-2004_04 |