HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiazolidine → (S)-N-[5-Amino-6-oxo-(1,3-thiazolidin-3-yl)-hexyl]-N-methyl-methanesulphonamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiazolidine | HCID 10444 | — |
| Reactant | 2-Nitrobenzenesulfonyl chloride | HCID 15540 | — |
| Reactant | Boc-Lys(Z)-OH | HCID 2724765 | — |
| Product | (S)-N-[5-Amino-6-oxo-(1,3-thiazolidin-3-yl)-hexyl]-N-methyl-methanesulphonamide hydrochloride | HCID 69890982 | — |
Reaction Steps
Starting from (S)-N6-(benzyloxycarbonyl)-N2-(tert-butyloxycarbonyl)-lysine, 2-nitrobenzenesulphonyl chloride and 1,3-thiazolidine, the expected product is obtained according to the procedure described in Steps A to C of Example 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716843B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-f7d97a3fa7034acd8e43003c8e1aa590 |
| Source note | uspto-grants-2004_04 |