Methanol → HCID 12085096, compound

Participants

Reaction Conditions

Reaction Steps

77.5 g (177 mmol) of the carboxylic acid prepared in stage 1 were added in portions to a solution of 65 ml of thionyl chloride (885 mmol) in 800 ml of methanol at a temperature of −15° C. to −10° C. The mixture was then stirred at 25° C. for 1 hour and at 50° C. for 1 hour.

Provenance & Evidence