HCID 22732048, compound → HCID 22732055, compound

HRID 2084047Notes

Reaction equation

HRID 2084047 reaction equation
[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][N:8]2[CH:11]2[CH2:16][CH2:15]N(C)[CH2:13][CH2:12]2)=[CH:4][CH:3]=1.BrC1C=CC(CC=[O:27])=C(NC2CCN(C)CC2)C=1>>[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][N:8]2[CH:11]2[CH2:16][CH2:15][O:27][CH2:13][CH2:12]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 22732048HCID 22732048, compoundHCID 86594076HCID 86594076, compound

Product 1

HCID 22732055HCID 22732055, compound

Procedure

6-Bromo-1-(N-methyl-piperidin4-yl)-indole; from 4-Bromo-2-[(N-methyl-piperidin-4-yl)amino]-phenylacetaldehyde, dimethyl acetal (108 mg, 0.30 mmol). Yield 69.4 mg (79%).

Sources & evidence

ORD record
ord-2a81fe5c2dbb4c96b41be4463ecf82fb
Source dataset
uspto-grants-2004_04
Patent number
US06716837B1

Reaction notes

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