HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-4-piperidone → HCID 10083756, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-4-piperidone | HCID 74049 | — |
| Reactant | 6-Bromoindole | HCID 676493 | — |
| Reactant | 4-(1H-indol-6-yl)-1-methyl-piperidin-4-ol | HCID 10130804 | — |
| Reactant | HCID 178418306 | HCID 178418306 | — |
| Product | HCID 10083756 | HCID 10083756 | — |
Reaction Steps
In a similar fashion, 6-[4-Hydroxy-1-methyl-piperidin-4-yl]-indole was prepared from 6-bromoindole (1.0 g, 5 mmol); KH (0.225 g, 5.6 mmol), 1.7M tBuLi (7.5 ml, 12.7 mmol) and N-methyl-4-piperidone (1.246 g, 10.9 mmol). Yield 0.382 g (35%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716837B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-6b1da4c988304079b5a1dc5569b8120c |
| Source note | uspto-grants-2004_04 |