HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrabutylammonium Fluoride → HCID 69883381, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| Reactant | HCID 69883351 | HCID 69883351 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 69883381 | HCID 69883381 | 73% |
Reaction Steps
To a solution of 6-(N-methylpiperazinyl)-1-triisopropylsilyl indole (237 mg, 0.64 mmol) in 1 ml of THF, 1M TBAF (0.64 ml, 0.64 mmol) was added dropwise at room temperature. After 30 mins, the mixture was diluted with dichloromethane and washed 3 times with water to give the title product (100.6 mg, 73% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716837B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-4defd6d3cab841d9865d5ca496045eac |
| Source note | uspto-grants-2004_04 |