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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2084076Generated: October 30, 2026

3-Methoxyaniline → HCID 22732377, compound

https://huagongshe.com/reaction/2084076

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxyanilineHCID 10824—
Reactant4-chloro-6-methyl-2-(3-methylphenyl)pyrimidineHCID 4189212—
ProductHCID 22732377HCID 22732377—

Reaction Steps

The title compound was prepared from 4-chloro-6-methyl-2-(3-methylphenyl)pyrimidine (100 mg, 0.457 mmol) and m-anisidine (51 μl, 0.457 mmol) similar to Example 11 as a pale yellow solid (11 mg, 8%). 1H NMR (DMSO-d6): 8.09 (s, 1H), 8.05 (d, J=7.5 Hz, 1H), 7.54-7.49 (m, 4H), 7.35 (t, J=8.1 Hz, 1H), 7.21 (s, 1H), 6.78 (s, 2H), 3.81 (s, 3H), 2.43 (s, 6H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06716851B2
Source datasetuspto-grants-2004_04
ORD IDord-0f8710f361684042847ee848c65e7c11
Source noteuspto-grants-2004_04