m-Toluidine → 4-(3-Methylanilino)-6-methyl-2-(2-pyridinyl)pyrimidine

Beteiligte Stoffe

Reaktionsschritte

The title compound was prepared from 4-chloro-6-methyl-2-(2-pyridinyl)pyrimidine (100 mg, 0.486 mmol) and m-toluidine (52 μl, 0.486 mmol) similar to Example 13 and isolated as a pale yellow oil (132 mg, 99%). 1H NMR (CDCl3): 8.76-8.74 (m, 1H), 8.43-8.40 (m, 1H), 7.78-7.72 (m, 1H), 7.55 (s, 1H), 7.31-7.08 (m, 4H), 6.92 (d, J=7.2 Hz, 1H), 6.55 (s, 1H), 2.41 (s, 3H), 2.30 (s, 3H).

Herkunft & Nachweise