反应详情

The title compound was prepared from a mixture of 4-chloro-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.193 mmol) and 5-fluoro-2-methylaniline (36 mg, 0.290 mmol) similar to Example 58 and isolated as a tan solid (4 mg, 6%). 1H NMR (CDCl3): 9.71 (dd, J=0.80, 2.3 Hz, 1H), 8.74-8.71 (m, 1H), 8.68 (dd, J=1.7, 5.0 Hz, 1H), 7.72 (s, 1H), 7.44-7.39 (m, 1H), 7.33-7.28 (m, 2H), 7.02-6.95 (m, 1H), 6.67 (s, 1H), 2.29 (s, 3H).