3-Ethylaniline → HCID 22732464, compound

Participants

Reaction Steps

The title compound was prepared from a mixture of 4-chloro-2-(2-pyridinyl)-6-(trifluoromethyl)pyrimidine (25 mg, 0.096 mmol) and 3-ethylaniline (18 μl, 0.144 mmol) similar to Example 92 and isolated as a yellow oil (12 mg, 36%). 1H NMR (CDCl3): 8.84-8.82 (m, 1H), 8.57-8.54 (m, 1H), 7.89-7.84 (m, 1H), 7.72 (s, 1H), 7.44-7.40 (m, 1H), 7.34 (d, J=8.7 Hz, 1H), 7.14-7.11 (m, 3H), 7.01 (s, 1H), 2.69 (q, J=7.8 Hz, 2H), 1.27 (t, J=7.8 Hz, 3H).

Provenance & Evidence