Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2084147Generated: October 30, 2026

3-Aminophenol → HCID 22732425, compound

https://huagongshe.com/reaction/2084147

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-AminophenolHCID 11568—
Reactant4-Chloro-2-(2-pyrazinyl)-6-(trifluoromethyl)pyrimidineHCID 22732367—
ProductHCID 22732425HCID 22732425—

Reaction Steps

The title compound was prepared from a mixture of 4-chloro-2-(2-pyrazinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.192 mmol) and 3-aminophenol (31 mg, 0.288 mmol) similar to Example 97 and isolated as a tan solid (28 mg,). 1H NMR (DMSO-d6): 10.26 (s, 1H), 9.62 (s, 1H), 9.51-9.50 (m, 1H), 8.87-8.83 (m, 2H), 7.30 (s, 1H), 7.23-7.21 (m, 3H), 6.57-6.54 (m, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06716851B2
Source datasetuspto-grants-2004_04
ORD IDord-2a6cb1cb90ad4e17a40211fd9ff21272
Source noteuspto-grants-2004_04