HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminophenol → HCID 22732507, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminophenol | HCID 11568 | — |
| Reactant | 4-Chloro-2-(pyridin-4-yl)-6-(trifluoromethyl)pyrimidine | HCID 1485989 | — |
| Product | HCID 22732507 | HCID 22732507 | — |
Reaction Steps
The title compound was prepared from a mixture of 4-chloro-2-(4-pyridinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.193 mmol), 3-aminophenol (32 mg, 0.290 mmol) similar to Example 97 and isolated as a yellow solid (37 mg, 52%). 1H NMR (DMSO-d6): 10.51 (s, 1H), 8.98 (d, J=6.0 Hz, 2H), 8.54 (d, J=6.6 Hz, 2H), 7.32-7.21 (m, 5H), 6.61-6.57 (m, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716851B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-639b639e61814b25adf0300c6025feff |
| Source note | uspto-grants-2004_04 |