HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dimethylaniline → HCID 22732515, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dimethylaniline | HCID 7949 | — |
| Reactant | 4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine | HCID 1485990 | — |
| Product | HCID 22732515 | HCID 22732515 | — |
Reaction Steps
The title compound was prepared from a mixture of 4-chloro-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.193 mmol) and 3,5-dimethylaniline (36 μl, 0.290 mmol) similar to Example 117 and isolated as a yellow solid (26 mg, 39%). 1H NMR (CDCl3): 9.66-9.64 (m, 1H), 8.73 (s, 1H), 8.72-8.69 (m, 1H), 7.44-7.40 (m, 1H), 7.30 (s, 1H), 7.04 (s, 2H), 6.93 (s, 1H), 6.90 (s, 1H), 2.38 (s, 3H), 2.37 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716851B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-b6f5d95cda2c4c84a8acd83de170ee01 |
| Source note | uspto-grants-2004_04 |