HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminoindole → HCID 22732346, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminoindole | HCID 583431 | — |
| Reactant | 4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine | HCID 1485990 | — |
| Product | HCID 22732346 | HCID 22732346 | — |
Reaction Steps
The title compound was prepared from a mixture of 4-chloro-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.193 mmol) and 4-aminoindole (38 mg, 0.290 mmol) similar to Example 117 and isolated as a tan solid (6 mg, 9%). 1H NMR (CDCl3): 9.75-9.74 (m, 1H), 8.77-8.73 (m, 1H), 8.69 (dd, J=1.8, 5.1 Hz, 1H), 8.57 (s, 1H), 8.08 (s, 1H), 7.44-7.38 (m, 2H), 7.31-7.23 (m, 3H), 6.85 (s, 1H), 6.50-6.48 (m, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716851B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-6574029b30504d28a8306357e8f42ad7 |
| Source note | uspto-grants-2004_04 |