4-Chloro-2,5-dimethoxyaniline → HCID 22732435, compound

Participants

Reaction Steps

The title compound was prepared from a mixture of 4-chloro-2-(2-pyridinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.193 mmol) and 4-chloro-2,5-dimethoxyaniline (54 mg, 0.290 mmol) similar to Example 117 and isolated as a brown solid (58 mg, 73%). 1H NMR (CDCl3): 8.84-8.82 (m, 1H), 8.61-8.57 (m, 1H), 7.93-7.87 (m, 1H), 8.50 (bs, 1H), 7.66 (s, 1H), 7.49-7.45 (m, 1H), 7.02 (s, 1H), 7.01 (s, 1H), 4.07 (s, 3H), 3.92 (s, 3H).

Provenance & Evidence